Tag Archives: Studies

Connection Between Vitamin B3 and Skin Cancer – Vine Vera Reviews

You know how to take care of your skin. Keep it clean, moisturize and every time you anticipate sun exposure you should use a broad-spectrum sunscreen. What you might not know is that you may be able to reduce your risk of skin cancer with a vitamin.

Dermatologist examining a woman's skin for cancer.

The Study
An Australian study focused on the link between skin cancer and vitamin B3. The deadliest skin cancer is melanoma, and melanoma was not the focus of this study. Rather, this study focused on basal and squamous cell cancers which are two very common forms of skin cancer. Basal and squamous cell skin cancers are very rarely fatal, though they are persistent cancers that can continue to return time and again. The study involved 386 individuals who had suffered from at lest two skin cancer in the previous five years. The 386 people were split into two groups and one group was given 500 milligrams of vitamin B3 to take twice daily while the other group received placebo tablets to take twice daily.

The Results
Participants in this study had to continue vitamin use twice a day for an entire year. Until the very end of the research neither participant nor doctor knew who had been given vitamin B3 and who had been given the placebo. The findings suggest that taking vitamin B3 did reduce the rates of skin cancer. Additionally, vitamin B3 helped reduce the rate of pre-cancerous skin growths known as actinic keratoses.

Participants in the study were followed for an additional six months to see whether the vitamins provided a lasting effect once they were no longer being taken. The research indicated that the return rate of cancers was about equal in both the placebo and vitamin group indicating that in order for the vitamin to be a viable help, it must be taken continuously.

The Implications
Dr. Richard Schilsky of the American Society of Clinical Oncology stated that the study must be taken for what it is and that much more research will be needed. He also noted that Australians have higher rates of skin cancer than nearly anywhere else in the world. However, he did find it encouraging that the nicotinamide, the specific vitamin in B3, could be an alternative to the more costly procedures of removing skin cancers. Because basal and squamous cell skin cancers tend to reappear, the cost of surgery, freezing or radiation can become quite high.

The Australian researchers also warned that this study was not intended to make people with no previous history of basal and squamous cell skin cancers run out to begin taking vitamins. The only research conducted so far was among participants who already had skin cancers. The researchers theorize that nicotinamide is beneficial because it helps to repair the DNA of cells that have been damaged by sun exposure.

While the research is both interesting and hopeful, for the present doctors and skin care experts recommend that you practice safe and sensible skin care habits. Always use a broad-spectrum sunscreen and be sure to reapply frequently. Taking good care of your skin is an important part of keeping your entire body healthy.

Skin Care Benefits of Malic Acid – Vine Vera Reviews

Chemical formula of malic acid.

Malic acid is an Alpha Hydroxy Acid (AHA) that is commonly found in a number of fruits and vegetables, particularly in apples. Malic acid is considered to be very beneficial for your skin care routine and is used in all sorts of skin care products and treatments. AHAs such as malic acid are well known in the world of skin care because of their ability to treat all sorts of skin conditions and offer numerous skin benefits. In this article, Vine Vera examines some of the most important skin care benefits of malic acid.

Before going into the benefits, let’s examine the science behind using skin care products that contain malic acid. A number of studies were published in the 1990s and 2000s, which indicated that malic acid could be immensely beneficial for one’s skin care regimen. These studies conducted numerous tests and trials and found that malic acid could reverse the signs of aging and also help in increasing the production of collagen. One of the most recent studies on malic acid was published in the Journal of Drugs in Dermatology in the year 2013. In this study, the researchers offered 36 people suffering from melasma a regimen that included topical applications of malic acid and vitamin C. After a period of 2 – 6 months, the routine was discovered to be very effective in treating short-term melasma.

Now that you’re aware of the kind of wonders malic acid holds in store for your skin, Vine Vera helps you understand the specific skin care benefits of malic acid.

Gives you smoother looking skin – Adding malic acid into your topical skin care regimen can give you a less blotchy and smoother looking skin. Experts typically recommend you to use gentle cleansers on a day-to-day basis for cleansing, but if you’re searching for something that is gentle as well as effective, look for cleansers that contain ingredients such as malic acid, lactic acid, salicylic acid or glycolic acid.

Exfoliates your skin – You might have heard of Cleopatra bathing in spoiled milk to enjoy the exfoliation properties of lactic acid. Turns out that malic acid can offer similar benefits to your skin. This ingredient is commonly used in at-home peels as well as chemical peels because it has a thinning effect on the outermost layer of your skin. This means that malic acid can burn away the dead skin cells from the outermost layer of your skin, thereby allowing the younger and newer skin cells to shine through. What makes malic acid so special is that it has similar properties when compared to glycolic acid (another AHA), but is known to be less irritating to your skin.

Treatments for common skin issues – Products that contain malic acid can also be used as treatments for common skin issues such as age spots, rosacea, acne and scarring. Since the acid stimulates the growth of collagen, it promotes younger and smoother skin to shine through. This automatically reduces your skin issues and gives your skin a healthier, younger and softer feel.

Wine Benefits Increased by Jail Breaking Yeast? Vine Vera Reviews

A wine bottle and grapes on table with a brick wall background

Researchers have long explored the various benefits that wine has to offer to the human body. Modern day science has already come a long way in proving some of the benefits that red wine ingredients such as resveratrol offer to the skin and the body. Vine Vera came across a recent study conducted by researchers working for the University of Illinois that showed exciting findings on the health benefits of wine. This study was published in the Applied and Environmental Microbiology Journal.

According to researchers, jail breaking yeast could dramatically increase wine’s health benefits by reducing the toxic byproducts which often lead to headaches the next morning. Most fermented food items such as bread, beer and wine are made using a polyploid strain of yeast. This means that the products contain numerous copies of genes in their genomes. Yong-Su Jin, the principal investigator and associate professor at Energy Biosciences Institute, mentions that genetic engineering of polyploid strains was considered to be a difficult process because altering a gene in a single copy of the genome was rendered useless by the unaltered copy. The unaltered version of the genome brought back the altered gene into its original state.

Through this study, scientists managed to create a “genome knife” that could be used to cut through different copies of the targeted gene in a precise manner until all copies of the gene were cut. Researchers used this RNA-guided Cas9 nuclease to engineer the polyploid strains that are currently being used in the fermentation of beer and wine

Vine Vera discovered that the results obtained through the study have been astonishing. The researchers mention that wine already contains a healthy component called resveratrol. By adding engineered yeast into the picture, they managed to increase the amount of resveratrol by at least 10 times. Moreover, the engineered yeast also allowed researchers to add metabolic pathways that led to the introduction of other bioactive compounds such as ginseng into the wine yeast from different food items. Similarly, researchers also devised ways to transfer the resveratrol-producing pathways into the engineered strains of yeast that were used in the fermentation of beer, kimchee, kefir, pickles and cheese.

Another major benefit of this engineered yeast is that it allows winemakers to clone the enzyme which helps in enhancing the malolactic fermentation, a secondary process that is used to give the wine a smoother taste. Improper malolactic fermentation is one of the root causes of hangover symptoms and toxic byproducts. Yong-Su Jin also suggested that this “genome knife” could be used as a tool that allowed genetic engineers to crease precise mutations, something that was not possible before.

Designed mutations are important because they allow scientists to understand the functions of specific genes. Jin gives the examples of a yeast that creates a great wine flavor. It would be important to understand the reasons behind the flavor. This process can allow researchers to delete genes one by one, until that distinct flavor in the wine disappears, thereby isolating the gene responsible for giving the wine its flavor.

Vine Vera believes that such technologies should make genetically modified organisms less objectionable. Researchers have traditionally used antibiotic markers as a means of indicating the genetic alterations in organisms and people have objected to the use of such food items because of the dangers associated with enhanced antibiotic resistance. However, by using the “genome knife” concept, researchers should be able to precisely cut the genome, without having to resort to the use of antibiotic markers as a means of confirming the genetic event.

Vine Vera Reports: New Collagen Study – Vine Vera Reviews

Human collagen cells Human and animal bodies owe their strength to a structural protein that is better known as collagen. Collagen is found in abundance in the skin, the tendons, the bones and the ligaments. Vine Vera came across a new collagen study that was conducted by scientists working for the Massachusetts Institute of Technology in Cambridge and the researchers at the Max Planck Institute of Colloids and Interfaces in Potsdam-Golm. According to this study, water is intrinsic to body strength and the maintenance of collagen in the body. The study was also published in the Nature Communications Journal in the month of January 2015.

This study has shown that removing water from the collagen fibers in the body can have dramatic effects on the nanoscopic and molecular features. The findings of this study should help researchers in developing innovative materials because they suggest that collagen plays a more active role in living organisms than what was previously believed. In fact, collagen not only acts as a stabilizing framework, but also helps to generate tension during bone synthesis.

Collagen is known to have a hierarchical structure that consists of an extremely complex arrangement of molecules. These molecules act as the building blocks for collagen and are shaped like a rope, with three proteins twisted around each other. A majority of these ropes further combine to form a thick coil known as the Collagen fibrils. Numerous fibrils combine with each other to form the actual collagen fiber.

The researchers of this study investigated the characteristics of collagen and determined how the function of collagen is influenced by water. What makes this study so unique is that it combined a number of methods to investigate collagen at different levels of its hierarchy while controlling the water content of the natural material.

The results that were obtained were analyzed and compared with computer models of collagen fibrils that were developed as a part of the study. This approach actually helped the researchers to investigate the effects of water on the collagen structure in great details. According to Admir Masic, one of the authors of the study, water proved to be an integral component of collagen and it accounted for approximately 60% of collagen in terms of weight. The researchers used a process known as X-ray diffraction and revealed that the water molecules bind themselves to collagen. Therefore, it came as no surprise that the removal of water from collagen had dramatic effects. Reducing the water content practically forced the collagen to dry out, shortened the collagen molecules by 1.3% and the collagen fibrils by 2.5%.

Armed with this knowledge, researchers should actually be able to develop materials that behave in the opposite way when water is removed from them. As such, these findings could also be extremely useful when it comes to the fabrication of parchments and leather and enhancing their preservation. Moreover, Vine Vera discovered that the results are not just important from the engineering point of view. Although such levels of dehydration don’t occur in living organisms, the team found that removing water can be large enough, even under normal biological conditions, for the collagen to generate the same amount of tensile force as human muscles. The researchers now plan to investigate the physiological role that collagen contraction plays in various tissues.

Can Resveratrol Help Diabetes? Vine Vera Reviews

Diabetes medical research includes Resveratrol

Resveratrol, your friendly red wine component, has been attributed to all sorts of wonderful things like protection from free radical damage and antioxidant properties to anti-inflammatory properties and health benefits. Resveratrol is usually found in red wine and in the skin of red grapes and it is commonly derived from a plant called Japanese knotsweed as well. Previous studies have already found Resveratrol to offer all sorts of health benefits. Vine Vera reviewed one study that was conducted in the year 2012 which showed that Resveratrol helped in balancing issues when administered in a group of mice. Another study that was conducted in the year 2011 also showed that Resveratrol countered the effects of inability and helped the body to stay physically active. Other studies on Resveratrol have found that the compound works wonders in protecting the body from obesity and also reduces the risks of blood clotting. It now seems that Resveratrol might also be beneficial in helping patients suffering from Type 2 diabetes mellitus.

This revelation was made by a group of researchers in a review that was published in the Molecular Nutrition and Food Research Journal. According to this review, Resveratrol was found to be extremely effective in treating the Type 2 diabetes mellitus in animal models. The evidence from the study also suggests that Resveratrol might actually benefit Type 2 diabetes as well. This review that was conducted by the researchers is actually based on a group of studies that examined a total of 196 type 2 diabetes mellitus patients. These studies had found Resveatrol to act as an adjunct to pharmaceutical intervention of the Type 2 diabetes mellitus. The studies had also shown Resveratrol to be very effective in lowering hemoglobin A1c, systolic blood pressure and creatinine concentrations.

That being said, the studies didn’t find Resveratrol to have an effect on low density lipoprotein cholesterol, fasting glucose, high density lipoprotein cholesterol, diastolic blood pressure, triglycerides, insulin and homeostatic model assessment of insulin resistance. The studies didn’t find any adverse effects of Resveratrol in the Type 2 diabetes mellitus patients either.

Vine Vera reviewed another study that was published in the Natural Medicine Journal. The researchers associated with this study used a placebo-controlled, double-blind trial to examine the effects of Resveratrol in lowering the blood glucose and its related outcomes. The trial focused on 66 participants (33 men and 33 women) who had Type 2 diabetes. All subjects were assigned to receive 500mg of Resveratrol or placebo tablets for a period of 45 days. Once the outcomes were assessed, it was determined that Resveratrol treatments significantly decreased the systolic blood pressure, the fasting blood glucose, insulin as well as hemoglobin Ac1. No adverse effects of Resveratrol administration were found.

Moreover, Resveratrol is also known to help in preventing insulin resistance, a condition that makes the body less sensitive to the effects of insulin. Insulin resistance has already been termed as a precursor to diabetes. A number of rodent studies further confirmed that Resveratrol can help against the effects of an unhealthy lifestyle and bring about an increased longevity. Mice with a high-calorie diet actually managed to live longer after being given Resveratrol supplements.