Tag Archives: Resveratrol study

Can Resveratrol Help Diabetes? Vine Vera Reviews

Diabetes medical research includes Resveratrol

Resveratrol, your friendly red wine component, has been attributed to all sorts of wonderful things like protection from free radical damage and antioxidant properties to anti-inflammatory properties and health benefits. Resveratrol is usually found in red wine and in the skin of red grapes and it is commonly derived from a plant called Japanese knotsweed as well. Previous studies have already found Resveratrol to offer all sorts of health benefits. Vine Vera reviewed one study that was conducted in the year 2012 which showed that Resveratrol helped in balancing issues when administered in a group of mice. Another study that was conducted in the year 2011 also showed that Resveratrol countered the effects of inability and helped the body to stay physically active. Other studies on Resveratrol have found that the compound works wonders in protecting the body from obesity and also reduces the risks of blood clotting. It now seems that Resveratrol might also be beneficial in helping patients suffering from Type 2 diabetes mellitus.

This revelation was made by a group of researchers in a review that was published in the Molecular Nutrition and Food Research Journal. According to this review, Resveratrol was found to be extremely effective in treating the Type 2 diabetes mellitus in animal models. The evidence from the study also suggests that Resveratrol might actually benefit Type 2 diabetes as well. This review that was conducted by the researchers is actually based on a group of studies that examined a total of 196 type 2 diabetes mellitus patients. These studies had found Resveatrol to act as an adjunct to pharmaceutical intervention of the Type 2 diabetes mellitus. The studies had also shown Resveratrol to be very effective in lowering hemoglobin A1c, systolic blood pressure and creatinine concentrations.

That being said, the studies didn’t find Resveratrol to have an effect on low density lipoprotein cholesterol, fasting glucose, high density lipoprotein cholesterol, diastolic blood pressure, triglycerides, insulin and homeostatic model assessment of insulin resistance. The studies didn’t find any adverse effects of Resveratrol in the Type 2 diabetes mellitus patients either.

Vine Vera reviewed another study that was published in the Natural Medicine Journal. The researchers associated with this study used a placebo-controlled, double-blind trial to examine the effects of Resveratrol in lowering the blood glucose and its related outcomes. The trial focused on 66 participants (33 men and 33 women) who had Type 2 diabetes. All subjects were assigned to receive 500mg of Resveratrol or placebo tablets for a period of 45 days. Once the outcomes were assessed, it was determined that Resveratrol treatments significantly decreased the systolic blood pressure, the fasting blood glucose, insulin as well as hemoglobin Ac1. No adverse effects of Resveratrol administration were found.

Moreover, Resveratrol is also known to help in preventing insulin resistance, a condition that makes the body less sensitive to the effects of insulin. Insulin resistance has already been termed as a precursor to diabetes. A number of rodent studies further confirmed that Resveratrol can help against the effects of an unhealthy lifestyle and bring about an increased longevity. Mice with a high-calorie diet actually managed to live longer after being given Resveratrol supplements.

Vine Vera Reports: Studies Show that Resveratrol Protects DNA – Vine Vera Reviews

DNA strands affected by Resveratrol

Resveratrol, the red wine antioxidant that is known to offer wonderful solutions for your skin care, has also shown to activate an ancient stress response mechanism in your cells that allow them to guard themselves against DNA damage. Vine Vera came across a study that was conducted by the scientists from the Scripps Research Institute, which explained the health benefits that have attributed to Resveratrol, a compound that is found in the skin of red grapes and in red wine.

According to the study, lower levels of Resveratrol are more than sufficient to activate the stress response system in your skin. These levels are far lower than what was previously believed and the study itself helps to clear up a lot of mystery that initially surrounded Resveratrol and the benefits that it had to offer.

Vine Vera found this study published in the Nature Journal. The study re-builds on the recent research conducted by the Scripps Research Institute, which had discovered the existence of unique mechanisms that were associated with the enzymes being studied. Resveratrol has already been attributed to the famous “French Paradox”. According to this paradox, people in France enjoy a lower cardiovascular disease rate despite their high saturated fat diet. One of the many problems in discovering the benefits that Resveratrol had to offer was to determine the correct dosage required to enjoy the benefits. Laboratory experiments had shown the need for large doses of Resveratrol in order to make it beneficial, yet the quantities consumed were tiny. This inconsistency in the argument was actually termed as the “Resveratrol Paradox”. However, thanks to the recent research from Scripps, solutions to this paradox seem to have finally been found.

The confusing results led people to challenge the French Paradox itself and the evidence of fraud tainted some of the Resveratrol research. However, despite these problems, Resveratrol continued to show amazing results when used in mice or on humans and it was shown to actually offer significant benefits. One trial showed it improved blood circulation in the human brain and helped to fight Alzheimer’s, another study found that it triggers a stress response system by targeting the tRNA synthetases enzyme and other studies found that it offered antioxidant and anti-inflammatory properties to the skin. The Schimmel lab finally cleared the mystery by confirming that Resveratrol was actually beneficial for the human body because there exists a molecular resemblance between tyrosine and the chemical and this allows it to easily fit into the TyrRS binding pockets that tryrosine tends to occupy. The resulting TyrRS/ Resveratrol complex migrates into the cell nucleus and attaches itself to the PARP-1 protein, a protein that is already known to be involved in the stress response system of the human body.

According to the research conducted by Scripps, Resveratrol triggers a response system that has been deeply imbibed into the genes and dates back to hundreds of millions of years ago. Sajish, the first author of the study, mentions that it is conceivable that moderate amounts of red wine would actually offer enough Resveratrol to evoke the protective effects that can be found using this pathway. Derek Lowe, a medicinal chemist, also found the study to be fairly convincing.

Studies Show that Resveratrol Protects the Body – Vine Vera Reviews

A blond medical or scientific researcher or doctor using looking at a clear solution in a laboratory with her Asian female colleague out of focus behind her. By now, most of you are already aware about the wonders that Resveratrol, an anti-aging ingredient found in the skin of red grapes, has to offer. Researchers have long tried to determine exactly how Resveratrol manages to offer all sorts of skin and health benefits to the human body. Vine Vera was delighted to come across a new study, which actually proposed that the compound stimulates a stress response gene that ends up activating a number of genes that protect the body. Vine Vera found this study published in the Nature Journal. The study was conducted by a research team from The Scripps Research Institute in La Jolla, CA. According to the researchers of this study, two glasses of wine can trigger the stress response which is ultimately responsible for offering you with the health benefits that Resveratrol has to offer. Previous research has already associated Resveratrol with reduced cardiovascular diseases and longevity. A study which proved that Resveratrol could also help with the treatments of certain types of cancers was also published recently. There were a few studies that blasted the health benefits of Resveratrol by stating that people consuming Resveratrol were no closer to reduced risk of cancer when compared to people who consumed small amounts of the ingredient. Paul Schimmel, the senior investigator of this study, noted that most of these researchers had questioned the use of “unrealistically high doses of Resveratrol”. In this latest study, the group of researchers tried to determine if and how Resveratrol offered the human body with health benefits. The group investigated the compound’s association with the tRNA Synthetases, an enzyme that helps in translating the genetic material during protein synthesis. The researchers particularly focused on TyrRS, an enzyme that binds itself to Tyrosine, an amino acid, before linking with the genetic material. The group basically wanted to examine whether TyrRS was a target for Resveratrol because the compound had already shown to have properties that were similar to Tyrosine. The group also believed that the compound produces stress-response pathway in plant cells and it actually triggers a similar response in human cells. The experts used X-ray crystallography, amongst other tests, to compare the compound with TyrRS and determined that the compound actually mimics Tyrosine, to get TyrRS to bind with it. The researchers explained that it was this particular attachment that led the TyrRS away from the protein translation activity and pushed it closer to the cell nucleus. Once in the nucleus, this combination of Resveratrol and TryRS switched on the PARP-1 gene, a gene that is known to play a major role on aging, stress response and DNA repair. What’s more, the study also discovered that the PARP-1 gene switched on a number of other protective genes such as the SIRT6, p53 and FOXO3A. Vine Vera believes that these findings are actually very important for future Resveratrol studies because they offer a fundamental mechanism that showcases the beneficial effects of Resveratrol. Based on the results of this study, it can safely be assumed that taking moderate amounts of Resveratrol can actually offer a person with all sorts of health and skin related benefits.