Vine Vera came across a study conducted by researchers at the Linus Pauling Institute, Oregon State University. According to the results of this study, resveratrol (a compound found in red wine and in the skin of red grapes) and pterostilbene (a compound found in blueberries) stood out because of their ability to boost the human innate immune system. Both compounds worked in combination with vitamin D and they had a tremendous impact in raising the expression of the CAMP gene, a gene that is involved with the immune functions of the body. The research was published in the Molecular Nutrition and Food Research Journal and has been supported by the National Institutes of Health.
Despite the interest in stilbenoids like pterostilbene and resveratrol, their bioavailability is in doubt. The researchers believe that some of their applications may even offer topical solutions to improve the barrier defense in infections and wounds. Stilbenoids are basically compounds that are produced by plants as a means of fighting infection. This research goes on to show that combining stilbenoids with vitamin D will have a better impact than any of these compounds would offer individually.
The study analyzed 446 different compounds for their ability to boost the immune system. According to Adrian Gombart, an associate professor at the OSU College of Science, these two compounds stood out from among the hundreds that were tested. He mentions that their synergy with vitamin D in terms of increasing the expression of the CAMP gene was intriguing and significant.
Resveratrol has already been subjected to all sorts of studies to examine its possible benefits, and it seems as if the compound keeps coming up with new benefits every now and then. From fighting cancer and improving cardiovascular health to protecting the skin and reducing inflammation, this compound really has it all.
The CAMP gene has also been subjected to all sorts of studies because of the fact that it is known to play a huge role in the innate immune system, also known as the first line of defense of the human body when it comes to combating bacterial infection. The response of the immune system is particularly important in the modern world as a number of antibiotics are beginning to lose their effectiveness. The regulation of this gene by vitamin D was discovered by Gombart, but researchers are still finding out more about how compounds affect immune functions.
The research conducted by Oregon State University scientists is the first one to show a proper synergy with vitamin D that helped in increasing the CAMP gene by several times. However, all findings were made using laboratory cell cultures. Experts state that it is not necessary that dietary intake of these compounds would lead to similar results. That being said, this study certainly makes the potential that certain foods have to offer all the more interesting.
More research is required to understand things better. Continued research could also offer a better understanding of how nutrition and diet affect the immune system. This is expected to lead to the development of natural compounds that can work wonders in boosting the innate immune response.