By now, most of you are already aware about the wonders that Resveratrol, an anti-aging ingredient found in the skin of red grapes, has to offer. Researchers have long tried to determine exactly how Resveratrol manages to offer all sorts of skin and health benefits to the human body. Vine Vera was delighted to come across a new study, which actually proposed that the compound stimulates a stress response gene that ends up activating a number of genes that protect the body. Vine Vera found this study published in the Nature Journal. The study was conducted by a research team from The Scripps Research Institute in La Jolla, CA. According to the researchers of this study, two glasses of wine can trigger the stress response which is ultimately responsible for offering you with the health benefits that Resveratrol has to offer. Previous research has already associated Resveratrol with reduced cardiovascular diseases and longevity. A study which proved that Resveratrol could also help with the treatments of certain types of cancers was also published recently. There were a few studies that blasted the health benefits of Resveratrol by stating that people consuming Resveratrol were no closer to reduced risk of cancer when compared to people who consumed small amounts of the ingredient. Paul Schimmel, the senior investigator of this study, noted that most of these researchers had questioned the use of “unrealistically high doses of Resveratrol”. In this latest study, the group of researchers tried to determine if and how Resveratrol offered the human body with health benefits. The group investigated the compound’s association with the tRNA Synthetases, an enzyme that helps in translating the genetic material during protein synthesis. The researchers particularly focused on TyrRS, an enzyme that binds itself to Tyrosine, an amino acid, before linking with the genetic material. The group basically wanted to examine whether TyrRS was a target for Resveratrol because the compound had already shown to have properties that were similar to Tyrosine. The group also believed that the compound produces stress-response pathway in plant cells and it actually triggers a similar response in human cells. The experts used X-ray crystallography, amongst other tests, to compare the compound with TyrRS and determined that the compound actually mimics Tyrosine, to get TyrRS to bind with it. The researchers explained that it was this particular attachment that led the TyrRS away from the protein translation activity and pushed it closer to the cell nucleus. Once in the nucleus, this combination of Resveratrol and TryRS switched on the PARP-1 gene, a gene that is known to play a major role on aging, stress response and DNA repair. What’s more, the study also discovered that the PARP-1 gene switched on a number of other protective genes such as the SIRT6, p53 and FOXO3A. Vine Vera believes that these findings are actually very important for future Resveratrol studies because they offer a fundamental mechanism that showcases the beneficial effects of Resveratrol. Based on the results of this study, it can safely be assumed that taking moderate amounts of Resveratrol can actually offer a person with all sorts of health and skin related benefits.